A bit about me

Your patients are mine
and mine alone

3 million—

the number of adults who report having epilepsy.1

1.8 million—

the number of adults who are in my clutches, still having seizures even though they’re using AEDs.2

That’s right—1.8 million individuals, some of whom are undoubtedly your patients, are still living lives compromised by continued seizures. That’s about 60%. As in more than half.2

Are you surprised by that? Because you shouldn’t be.

Are you surprised by that?

Because you shouldn’t be.

Modern medicine doesn’t
scare me

Medicines

More than a dozen AEDs have tried to challenge me over the past 2 decades, but what difference has it made? The proportion of epilepsy patients who experience zero seizures today is nearly identical to what it was in the 1980s.3

But you keep on trying, don’t you? Treatment regimen after treatment regimen, you switch and swap AEDs in hopes that something—anything—would work as well as you had hoped. The fact remains that your chances of true success—as in zero seizures—grow slim after that first regimen fails.3

Probability of success (zero seizures) with subsequent regimens3,*:
2nd regimen

11.6%
increase

3rd regimen

4.4%
increase

≥4th regimen

<2%
increase

*Zero seizures, also known as seizure freedom, was defined as a patient experiencing no seizures for the previous 12 months or longer.3

Once I attack, my captives’
lives may fall to pieces

Just one episode in a
5-year span makes them4,:
Sandglass

Just one episode in a
5-year span makes them4,:

6x more

likely to have
depression

3x more

likely to have
poor health

4x more

likely to require
daily informal
assistance

4.5x more

likely to be
prevented
from driving

2x more

likely to have
limitations in
education

3x more

likely to have
limitations in
employment

4x more

likely to have
limitations in at
least 1 usual
activity

2x more

likely to
experience
stigma

Compared with those who have managed to live free from seizures for 5 years.4

Measured by a health perception tool.4

Witness my wrath
If you think this is the extent of my power, think again. There’s much more to come. Give me your contact info to keep up with what—and whois next.

AED=antiepileptic drug.

References: 1. Zack MM, Kobau R. National and state estimates of the numbers of adults and children with active epilepsy—United States, 2015. MMWR Morb Mortal Wkly Rep. 2017;66(31):821-825. 2. Tian N, Boring M, Kobau R, Zack MM, Croft JB. Active epilepsy and seizure control in adults—United States, 2013 and 2015. MMWR Morb Mortal Wkly Rep. 2018;67(15):437-442. 3. Chen Z, Brodie MJ, Liew D, Kwan P. Treatment outcomes in patients with newly diagnosed epilepsy treated with established new antiepileptic drugs: a 30-year longitudinal cohort study. JAMA Neurol. 2018;75(3):279-286. 4. Josephson CB, Patten SB, Bulloch A, et al. The impact of seizures on epilepsy outcomes: a national, community-based survey. Epilepsia. 2017;58(5):764-771.